Endocrine Abstracts

Introduction: Dopamine agonists have been reported to increase the risk of cardiac valve regurgitation in valve disease risks for 3 years treatment with cabergoline in patients with prolactinma. The aim of the study was to evaluate the frequency of cardiac valve diseases and regurgitation in patients with prolactinoma at the end of 3 years.Subjects and method: Thirty-one patients with prolactinoma who had received cabergoline following 3 years were enrol...

Introduction: Hyperthyroidism in the elderly can present with subtle nonspecific complaints. Patients with long-standing goiter can develop autonomous nodules resulting in toxic nodular goiter.Case report: An 86 year old women was referred from gastroenterologist for thyroid disease because of low TSH. She had diarrhea with five to eight bowel movements a day for six months. She denied palpitations, heat intolerance or muscle weakness. She had been noted...

Objective: The aim of our study was to investigate the relationships between insulin receptor substrat-1 (IRS-1) and insulin receptor substrat-2 (IRS-2) gene polymorphisms and cardiovascular factors such as blood pressures, BMI, LDL- cholesterol, triglyceride, HOMA-IR, homocysteine, hsCRP and fibrinogen levels in patients with metabolic syndrome (MetS).Subjects and methods: The study population included 100 patients with MetS and 30 patients without MetS...

Introduction: Biochemical and clinical vitamin B12 deficiency has been demonstrated to be highly prevalent among patients with diabetes mellitus. The aims of the study were 1. to compare the vitamin B12 (VB12) levels, and 2. to investigate the relationship between VB12, fasting insulin and HOMA-IR levels in elderly patients with metabolic syndrome (MetS).Subjects and method: Study population included 121 (mean age 64.3±14.1 years) (80 female, 41 mal...

Aims: The metabolic syndrome (MetS) is a summary measure of important CVD risk factors that frequently coexist. The syndrome is evident in 20–30% of middle-aged women and has been linked to the development of CVD and diabetes. The aim of the study was to examine the differences in demographic and clinical profiles among older (≥60 years) and younger (<60 years) patients with MetS.Methods: The study was included 45 older (mean age 63.1&#177...